Sickle Cell Anemia

Sickle carrel anemia is an inherited gillyflower disorder, characterized primarily by chronic anemia and periodic episodes of pain. The reach of reap hook carrell anemia is a genetic disorder in which the haemoglobin is defective. When the hemoglobin molecules gives up their oxygen, some will cluster to chafeher. This forms long, rod-like structures which cause the red simple eye booths to stiffen and assume a reap hook shape. With the deformity, the cubicles can non squeeze through the blood vessels, depriving organs and tissues of oxygen

Normal blood cells represent for about one hundred twenty day in the blood, while the defective sickled cells live only ten to twenty. Because of their runty lifespan, the blood is constantly deficient in red blood cells, a condition kn suffer as anemia.

Sickle cell anemia is a genetic disorder that resulted from a mutation which occurred thousands of geezerhood ago in Africa, the Mediterranean basin, the Middle East, and India. At the time, vitriolic malaria epidemics cause great numbers of deaths. Those who inherited the sickle cell gene had an advantage: unlike baberen with normal red blood cells, they could survive malaria, and grow old enough to have their own offsprings, thus passing along the mutation. As the population migrated, so did the mutation.



In countries where malaria is not a problem, like the United States, the sickle cell mutation is disorder, no longer providing a natural selection trait of value. Instead it is a serious threat. If a child inherits two of the recessive sickle cells genes, they will be innate(p) with sickle cell anemia .In the United States alone, sickle cell anemia affects approximately seventy-two thousand people, most of whose ancestors descended from Africa. around two million Americans carry the gene for sickle cell anemia.

The clinical course of sickle cell anemia does not follow a single pattern;...

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